Home / Topic / Genetic disorders
Topic Genetic disorders
Asked 3 times across 2 UPSC exams over 33 years (1992–2025), peaking in 1992.
Key insights
- Most tested in CSE — 2 of 3 PYQs
- Most asked in 1992
- Recurs across 3 years (1992–2025)
How it travelled across exams
First appearance in each exam — the same idea, reframed.
CSE 1992 → GEO 2025
How the concept evolved
Long-running — most appearances (2 of 3) predate 2016, and it still returns.
Related concepts
Ideas UPSC tests alongside this one — keep exploring.
Sample questions
You've seen the pattern — here are a few of the actual PYQs.
GEO2025
Which one of the following sets of diseases is example of polygenic disorders?
- A Sickle cell anaemia, Haemophilia, Hypertension
- B Hypertension, Coronary heart disease, Diabetes ✓
- C Duchenne muscular dystrophy, Colour blindness, Diabetes
- D Achondroplasia, Cystic fibrosis, Tay-Sachs disease
✓ Correct answer: (B)
Science & Technology › Biology & Health
CSE1993
Haemophilia is a hereditary disease carried by
- A females and expressed by females
- B females and expressed by males ✓
- C males and expressed by females
- D males and expressed by males
✓ Correct answer: (B)
Science & Technology › Biology & Health
CSE1992
Which one of the following diseases is caused due to defective genes?
- A Ulcer
- B ✓
- C Diabetes
- D Cancer
✓ Correct answer: (B)
Science & Technology › Biotech & Genetics
Study how UPSC repeats — not just the papers
₹199 / 1 year · Founding Member
Full access unlocks the three things no PYQ PDF gives you:
① Cross-exam learning — see the same idea recur across CSE, CAPF, CDS and NDA.
② Topic evolution — how each idea is framed, year by year.
③ Question intelligence — every PYQ + answer, linked to related concepts and similar questions.
e.g. Round Table Conference: CDS 2017 → CSE 2017 → … → CAPF 2024
15 days free, no card required — then ₹199 for 1 year.
Start your 15-day free trial →